Publications

With over 45 peer reviewed publications and 15 book chapters our veteirnary surgeons are committed to advancing the health of our canine companions. Below is just a subset of our publications.

Orthobiologics

Joint Replacement
Arthroscopy
Knee – Stifle – ACL

Hip Joint

Elbow Joint
Shoulder Joint
Limb Deformities
Orthopedic Imaging
Osteoarthritis
Achilles Tendon
Other Publications
ORTHOBIOLOGICS

Intra-articular Injectable Therapies.
Franklin SP and Kieves N. Canine and Feline Arthroscopy. Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025.

Randomized Controlled Trial Comparing Autologous Protein Solution to Hyaluronic Acid Plus Triamcinolone for Treating Hip Osteoarthritis in Dogs
Franklin, SP. Frontiers in Veterinary Science 2021 PMID: 34395580 PMCID: PMC8357414 DOI: 10.3389/fvets.2021.713768

A Pilot Clinical Study Assessing Treatment of Canine Hip Dysplasia using Autologous Protein Solution.
Franklin, SP. Frontiers in Veterinary Science 2019; 6:243 doi.org/10.3389/fvets.2019.00243

Biological Therapies in Canine Sports Medicine.
Pozzi A and Franklin SP. In Canine Sports Medicine and Rehabilitation. Second Edition. Editors Chris Zink and Janet B. Van Dyke. John Wiley & Sons, Inc. 2018. Chapter 16; pages 404-424.

Platelet-rich plasma and autologous conditioned serum. 
Saunders B, Bearden R, and Franklin SP.   In Veterinary Surgery: Small Animal. Second Edition. Editors KM Tobias and SA Johnston. Elsevier Health Sciences. 2018. Chapter 4; pages 40-48.

Assessment of Canine Autologous Conditioned Plasma™ Cellular and Transforming Growth Factor-β1 Content.
Franklin SP, Birdwhistell KE. Frontiers in Veterinary Science. 2018;11(5):105.
doi: 10.3389/fvets.2018.00105

Use of a cyclooxygenase-2 inhibitor does not inhibit platelet activation or growth factor release from platelet-rich plasma.
Ludwig HC, Brainard BM, Birdwhistell KE, Franklin SP. American Journal of Sports Medicine. 2017;45(14):3351-3357.
doi: 10.1177/0363546517730578

Sustained release of transforming growth factor-β1 from platelet-rich chondroitin sulfate glycosaminoglycan gels.
Birdwhistell KE, Karumbaiah L, Franklin SP. Journal of Knee Surgery. 2017.
doi: 10.1055/s-0037-1603801.

The effect of platelet-rich plasma on osseous healing in dogs undergoing high tibial osteotomy.
Franklin SP, Burke E, Holmes SP.  PLoS One. 2017; May 16;12(5):e0177597.
doi: 10.1371/journal.pone.0177597.

Influence of Cellular Composition and Exogenous Activation on Growth Factor and Cytokine Concentrations in Canine Platelet-Rich Plasmas.
Franklin SP, Birdwhistell KE, Strelchik A, Garner BC, and Brainard B.  Frontiers in Veterinary Science. April 5, 2017. https://doi.org/10.3389/fvets.2017.00040

Validation of commercial ELISAS for quantifying anabolic growth factors and cytokines in canine ACD-A anticoagulated plasma.
Birdwhistell KE, Basinger RW, Hayes BR, Norton NA, Hurley DJ, Franklin SP. Journal of Veterinary Diagnostic Investigation. 2017 Mar;29(2):143-147
doi: 10.1177/1040638717690186.

Characteristics of canine platelet-rich plasma prepared with five commercially available systems.
Franklin SP, Garner BC, and Cook JL.  American Journal of Veterinary Research, 2015; 76:822–827.

JOINT REPLACEMENT

Outcomes Associated with Osteochondral Allograft Transplantation in Dogs.
Franklin SP, Kim SE, Karlin M, Kowaleski MP, Murphy SM, Cross A, Gillick M, Stoker AM, Cook JL. Frontiers in Veterinary Science 2021

Clinical outcomes associated with the initial use of the Canine Unicompartmental Elbow (CUE) Arthroplasty System®
Cook JL, Schulz KS, Karnes J, Franklin SP, Canapp SO, Lotsikas P, Fitzpatrick N, Wheeler J, Gillick, M, Cross A, Walls C, Albrecht M, Williams JE, Crouch DT, Lewis DD, Pozzi A, Ridge P.  Canadian Veterinary Journal, 2015;56:971–977.

Comparison of Osteotomy Level with Three Different Canine Total Hip Replacement Systems.
Franklin SP, Franklin AL, Feyerabend N, Hayashi K, Miller NA, Cook JL. Open Veterinary Journal 2022; 12(6): 975-979.

Complications with the Zurich Canine Total Hip Replacement System in an Initial Series of Cases Performed by a Single Surgeon
Samuel P Franklin  Nathan A Miller  Todd Riecks Veterinary and Comparative Orthopaedics and Traumatology. 2021 Sep;34(5):346-351. doi: 10.1055/s-0041-1730366. Epub 2021 Jun 3

Risk factors for femoral prosthesis loosening in the Helica total hip replacement system.
Agnello, K, Cimino Brown D, Aoki K, Franklin S, Hayashi, K. Veterinary and Comparative Orthopaedics and Traumatology, 2015;28(1)48-53.

What is the evidence? Surgical Treatment of large dogs with hip joint osteoarthritis.
Franklin SP and Cook JL. Journal of the Veterinary Medical Association,2011;238(4):440-442.

ARTHROSCOPY

Small Animal Arthroscopy.
Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025

Arthroscopy Equipment
Franklin SP. Canine and Feline Arthroscopy. Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025.

Biology and Assessment of Articular Cartilage
Birdwhistell KE and Franklin SP. Canine and Feline Arthroscopy. Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025.

Focal Cartilage Injuries
Birdwhistell KE and Franklin SP. Canine and Feline Arthroscopy. Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025.

Complex Articular Surface Injuries
Franklin SP, Cook JL, Bottcher P. Canine and Feline Arthroscopy. Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025.

Arthroscopy.
Franklin SP and KS Schulz. In Veterinary Surgery: Small Animal. Second Edition. Editors KM Tobias and SA Johnston. Elsevier Health Sciences. 2018. Chapter 71; pages 1323-1347.

Comparison of ultrasonography and magnetic resonance imaging to arthroscopy for diagnosing medial meniscal lesions in dogs with cranial cruciate ligament deficiency.
Franklin SP, Cook JL, Cook CR, Shaikh L, Clarke KM, Holmes SP. Journal of the American Veterinary Medical Association. 2017.1;251(1):71-79. doi: 10.2460/javma.251.1.71.

KNEE – STIFLE – ACL

Magnetic resonance imaging diagnosis and arthroscopic treatment of medial meniscal injury in a dog with a palpably stable stifle.
Adams RW, Holmes SP, Franklin SP.  Canadian Veterinary Journal. 2018;59(6):654-658.

Surgical treatment of concurrent meniscal injury.
Franklin SP, Cook JL, and Pozzi A.  In Advances in the Canine Cranial Cruciate Ligament. Second Edition. Editor, Peter Muir. John Wiley & Sons, Inc. 2018. Chapter 35; pages 295-300.

The effect of platelet-rich plasma on osseous healing in dogs undergoing high tibial osteotomy.
Franklin SP, Burke E, Holmes SP.  PLoS One. 2017; May 16;12(5):e0177597. doi: 10.1371/journal.pone.0177597.

Meniscal injury in dogs with cranial cruciate ligament rupture. 
Franklin SP, Gilley RS, and Palmer RH. Compendium on continuing education for the practicing veterinarian, 2009;32(10):E1-E11.

Comparison of ultrasonography and magnetic resonance imaging to arthroscopy for diagnosing medial meniscal lesions in dogs with cranial cruciate ligament deficiency.
Franklin SP, Cook JL, Cook CR, Shaikh L, Clarke KM, Holmes SP. Journal of the American Veterinary Medical Association. 2017.1;251(1):71-79. doi: 10.2460/javma.251.1.71.

HIP JOINT

Comparison of Osteotomy Level with Three Different Canine Total Hip Replacement Systems.
Franklin SP, Franklin AL, Feyerabend N, Hayashi K, Miller NA, Cook JL. Open Veterinary Journal 2022; 12(6): 975-979.

Complications with the Zurich Canine Total Hip Replacement System in an Initial Series of Cases Performed by a Single Surgeon
Samuel P Franklin  Nathan A Miller  Todd Riecks Veterinary and Comparative Orthopaedics and Traumatology. 2021 Sep;34(5):346-351. doi: 10.1055/s-0041-1730366. Epub 2021 Jun 3

Risk factors for femoral prosthesis loosening in the Helica total hip replacement system.
Agnello, K, Cimino Brown D, Aoki K, Franklin S, Hayashi, K. Veterinary and Comparative Orthopaedics and Traumatology, 2015;28(1)48-53.

What is the evidence? Surgical Treatment of large dogs with hip joint osteoarthritis.
Franklin SP and Cook JL. Journal of the Veterinary Medical Association,2011;238(4):440-442.

Triple Pelvic Osteotomy and Double Pelvic Osteotomy in dogs.
Franklin SP.  In Veterinary Clinics of North America. 2017 Jul; 47(4):865-884. doi: 10.1016/j.cvsm.2017.02.005.

Randomized Controlled Trial Comparing Autologous Protein Solution to Hyaluronic Acid Plus Triamcinolone for Treating Hip Osteoarthritis in Dogs
Franklin, SP. Frontiers in Veterinary Science 2021 PMID: 34395580 PMCID: PMC8357414 DOI: 10.3389/fvets.2021.713768

A Pilot Clinical Study Assessing Treatment of Canine Hip Dysplasia using Autologous Protein Solution.
Franklin, SP. Frontiers in Veterinary Science 2019; 6:243 doi.org/10.3389/fvets.2019.00243

ELBOW JOINT

General Principles of Elbow Joint Arthroscopy.
Franklin SP. Canine and Feline Arthroscopy. Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025

Utility of MRI for characterizing articular cartilage pathology in dogs with medial coronoid process disease.
Franklin SP, Burke E, Holmes SP. Frontiers in Veterinary Science. February 24, 2017. 4:25. https://doi.org/10.3389/fvets.2017.00025

Theory and development of a unicompartmental resurfacing system for treatment of medial compartment disease of the canine elbow.
Franklin SP, Burke E, Holmes SP. Frontiers in Veterinary Science. February 24, 2017. 4:25. https://doi.org/10.3389/fvets.2017.00025

Clinical outcomes associated with the initial use of the Canine Unicompartmental Elbow (CUE) Arthroplasty System®
Cook JL, Schulz KS, Karnes J, Franklin SP, Canapp SO, Lotsikas P, Fitzpatrick N, Wheeler J, Gillick, M, Cross A, Walls C, Albrecht M, Williams JE, Crouch DT, Lewis DD, Pozzi A, Ridge P.  Canadian Veterinary Journal, 2015;56:971–977.

SHOULDER JOINT

Diagnosing medial shoulder instability.
Franklin SP. Veterinary and Comparative Orthopaedics and Traumatology. 2019; 32:v-vi.

Outcomes associated with treatments for medial, lateral, and multi-directional shoulder instability in dogs.
Franklin SP, Devitt C, Ogawa J, Ridge P, Cook JL. Veterinary Surgery, 2013;42(4):361-364.

LIMB DEFORMITIES

Correction of antebrachial angulation-rotation deformities in dogs with oblique plane inclined osteotomies.
Franklin SP, Dover R, Andrade N, Rosselli D. Vet Surg. 2017 Sep 14. doi: 10.1111/vsu.12706

ORTHOPEDIC IMAGING

Comparison of ultrasonography and magnetic resonance imaging to arthroscopy for diagnosing medial meniscal lesions in dogs with cranial cruciate ligament deficiency.
Franklin SP, Cook JL, Cook CR, Shaikh L, Clarke KM, Holmes SP. Journal of the American Veterinary Medical Association. 2017.1;251(1):71-79. doi: 10.2460/javma.251.1.71.

Magnetic resonance imaging diagnosis and arthroscopic treatment of medial meniscal injury in a dog with a palpably stable stifle.
Adams RW, Holmes SP, Franklin SP.  Canadian Veterinary Journal. 2018;59(6):654-658.

Utility of MRI for characterizing articular cartilage pathology in dogs with medial coronoid process disease.
Franklin SP, Burke E, Holmes SP. Frontiers in Veterinary Science. February 24, 2017. 4:25. https://doi.org/10.3389/fvets.2017.00025

OSTEOARTHRITIS

Intra-articular Injectable Therapies.
Franklin SP and Kieves N. Canine and Feline Arthroscopy. Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025.

Randomized Controlled Trial Comparing Autologous Protein Solution to Hyaluronic Acid Plus Triamcinolone for Treating Hip Osteoarthritis in Dogs
Franklin, SP. Frontiers in Veterinary Science 2021 PMID: 34395580 PMCID: PMC8357414 DOI: 10.3389/fvets.2021.713768

A Pilot Clinical Study Assessing Treatment of Canine Hip Dysplasia using Autologous Protein Solution.
Franklin, SP. Frontiers in Veterinary Science 2019; 6:243 doi.org/10.3389/fvets.2019.00243

Biological Therapies in Canine Sports Medicine.
Pozzi A and Franklin SP. In Canine Sports Medicine and Rehabilitation. Second Edition. Editors Chris Zink and Janet B. Van Dyke. John Wiley & Sons, Inc. 2018. Chapter 16; pages 404-424.

Managing Canine Osteoarthritis. Education Resources, University of Georgia (2016).
Content Contributors: Franklin SP, Figueiredo MD, Price GS, Marcellin-Little DJ, Moore JN, Pfeiffer S, Davis E, Obrin T, Herron CB. Sponsored by Merial.

ACHILLES TENDON

Patella tendon repair using a patellar tendon allograft and external fixator in three dogs. 
Tidwell SJ, Franklin SP Veterinary and Comparative Orthopaedics and Traumatology Open 2022; 5(2): e98-e102

Novel Achilles mechanism repair utilizing a tendon allograft and hybrid external fixator in dogs.
Tidwell SJ, Greenwood K, Franklin SP. Open Veterinary Journal. May-June 2022;12(3):335-340.

OTHER PUBLICATIONS

Special focus issue on patient centered orthopaedic care and research.
Cook JL and Franklin SP. Journal of Knee Surgery. 2023 36(14):1391. doi: 10.1055/s-0043-1773801

Pathophysiology and Treatment of Septic Arthritis.
Kowaleski M and Franklin SP. Canine and Feline Arthroscopy. Editors Franklin SP, Pozzi A, Schulz KS. Elsevier. Publication expected 2025.

Approach to the septic joint.
Franklin SP.  In Small Animal Surgical Emergencies. Editor Lillian R. Aronson. Wiley Blackwell, Ames, IA. 2016. Chapter 53; pages 523-532.

Metacarpophalangeal and metatarsophalangeal osteoarthritis in 49 dogs. 
Franklin SP, Park RD, Egger EL. Journal of the American Animal Hospital Association, 2009;45(3):112-117.

Rehabilitation and Physical therapy.
Martinez-Silvestre A and Franklin SP.  In Mader’s Reptile and Amphibian Medicine and Surgery. Third Edition. Editors SJ Divers and S Stahl. Elsevier Health Sciences.

Effect of propofol and ketamine-diazepam on intraocular pressure in healthy premedicated dogs.
Smith MD, Barletta M, Diehl KA, Hofmeister EH, Franklin SP. Vet Anaesth Analg. 2019;46(1):36-42. doi: 10.1016/j.vaa.2018.09.043.